PDGF+ Skin Rejuvenation in Costa Mesa

Advanced Growth Factor Therapy for Collagen Stimulation & Skin Rejuvenation

PDGF+ is an advanced regenerative treatment that stimulates collagen production, improves skin
quality, and enhances your skin’s natural regenerative processes.

Member Pricing

$810

Non Member Pricing

$900

Member Pricing

$990

Non Member Pricing

$1,100

PDGF+ Skin Rejuvenation
Ariessence®

PDGF+ (Platelet-Derived Growth Factor) is a naturally occurring growth factor that stimulates collagen production and supports your skin’s natural regenerative processes. By activating fibroblasts—the cells responsible for producing collagen—it helps improve skin firmness, texture, elasticity, and overall skin quality.

Pure PDGF+ delivers up to 300,000× the concentration of platelet-derived growth factor compared with PRP/PRF, providing an exceptionally concentrated regenerative signal to support collagen production and tissue remodeling.

• Maximizes collagen production
• Improves skin quality and texture
• Firms and strengthens aging skin
• Softens fine lines and crepey skin
• Enhances microneedling and LaseMD Ultra results

How PDGF+ Works

Collagen is the foundation of healthy, youthful-looking skin. As we age, collagen production naturally slows, contributing to fine lines, skin laxity, thinning skin, and changes in texture.

PDGF+ works at the cellular level by activating fibroblasts—the cells responsible for producing collagen and maintaining healthy skin. By enhancing your skin’s natural regenerative response, PDGF+ supports long-term collagen remodeling, helping improve skin quality, firmness, elasticity, and overall skin health.

Rather than simply hydrating the skin or temporarily improving its appearance, PDGF+ supports lasting skin rejuvenation by stimulating your body’s own collagen production.

What PDGF+ Treats

Fine Lines & Wrinkles

Stimulates collagen production to soften fine lines while improving skin firmness and elasticity.

Skin Texture & Tone

Improves overall skin quality, smoothness, texture, and radiance through collagen remodeling.

Skin Firmness

Supports stronger, healthier skin by rebuilding collagen and improving elasticity.

Crepey SkiN

Stimulates collagen remodeling to improve thinning, crepey skin on the face, neck, chest, under eyes, and hands.

Post-Laser & Microneedling Recovery

Enhances your skin’s natural regenerative response following microneedling and LaseMD Ultra while supporting collagen remodeling and skin rejuvenation.

Preventative Skin Rejuvenation

Supports long-term collagen production to help maintain firmer, healthier-looking skin before significant signs of aging develop.

Commonly Combined With

Who Is a Candidate?

PDGF+ is an excellent option for patients looking to:

• Improve skin quality
• Stimulate collagen naturally
• Reduce fine lines
• Improve skin firmness
• Improve crepey skin
• Enhance microneedling or LaseMD Ultra results
• Maintain healthier, more resilient skin over time

Treatment Areas

At LYVE Medspa, we use Pure PDGF+ to maximize your skin’s regenerative response.

Face

Improves overall skin quality, texture, fine lines, and firmness.

Under Eyes

Helps improve crepey skin, fine lines, and overall skin quality around the eyes.

Neck

Supports collagen production to improve skin texture and firmness.

Chest (Décolleté)

Improves sun-damaged, crepey skin while stimulating new collagen.

Hands

Helps improve thinning skin, texture, and visible signs of aging.

Why Choose PDGF+?

Unlike fillers, which restore lost volume, PDGF+ improves the quality of your skin by stimulating your body’s own collagen production.

 

Many regenerative treatments rely on your body’s natural concentration of growth factors. Pure PDGF+ provides an exceptionally concentrated source of platelet-derived growth factor, helping maximize collagen stimulation and support long-term skin rejuvenation.

 

Whether your goal is preventing early signs of aging, improving skin quality, or enhancing the results of microneedling or laser treatments, PDGF+ offers one of the most advanced regenerative approaches available.

The Treatment Process

What to Expect

Frequently Asked Questions

What is PDGF+?

PDGF+ (Platelet-Derived Growth Factor) is a naturally occurring growth factor that stimulates collagen production and supports your skin’s natural regenerative processes. It activates fibroblasts —the cells responsible for producing collagen—to improve skin quality, firmness, elasticity, and overall skin rejuvenation.

Pure PDGF+ is a pharmaceutical-manufactured recombinant form of Platelet-Derived Growth Factor (PDGF). Unlike PRP or PRF, it does not require a blood draw because the growth factor is produced through a standardized manufacturing process rather than being collected from your own blood. This allows for a highly concentrated and consistent source of PDGF to support collagen production and tissue regeneration.

PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are created from your own blood through a blood draw and centrifugation process. They contain multiple naturally occurring growth factors, but the concentration varies from person to person. Pure PDGF+ is a pharmaceutical-manufactured recombinant growth factor that does not require a blood draw. It delivers up to 300,000× the concentration of platelet-derived growth factor compared with PRP/PRF, providing a highly concentrated regenerative signal to support collagen production and tissue remodeling.

Both treatments stimulate the skin’s natural regenerative processes but work differently. PRP relies on your body’s own platelets and naturally occurring growth factors, while Pure PDGF+ provides a concentrated, standardized source of platelet-derived growth factor without requiring a blood draw. During your consultation, we’ll determine which treatment—or combination oftreatments—is most appropriate for your goals.

Yes. PDGF+ is commonly paired with microneedling to enhance collagen stimulation and improve skin quality. Microneedling creates controlled microchannels in the skin, allowing PDGF+ to support the skin’s natural regenerative response during the healing process.

Yes. PDGF+ is an excellent complement to LaseMD Ultra fractional laser. Applying PDGF immediately after treatment helps support collagen remodeling while enhancing skin rejuvenation.

No. PDGF+ does not add volume like dermal fillers. Instead, it improves the quality of your skin by stimulating your body’s natural collagen production.

Most patients benefit from a series of three to four treatments, followed by maintenance treatments based on their skin concerns and long-term goals.

Many patients begin noticing improvements in skin quality within several weeks. Because collagen remodeling is gradual, results continue to improve over the following two to six months